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Article

Production and purification of recombinant human BLyS mutant from inclusion bodies.

Protein expression and purification - 1 Jul 2005

Xue Xiaochang, Wang Zenglu, Yan Zhen, Shi Jihong, Han Wei, Zhang Yingqi

Abstract excerpt

B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor superfamily, is an important regulator of B cell homeostasis. In BLyS-deficient mice, B cell development is severely perturbed. On the other hand, mice transgenic for BLyS developed autoimmune disorders, such as increased germinal center formation, production of autoantibodies, and Ig deposition in kidneys. The overexpression of BLyS was found...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15886019
DOI: 10.1016/j.pep.2005.03.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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