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An improved yeast transformation method for the generation of very large human antibody libraries

3 Feb 2010

Abstract excerpt

Antibody library selection by yeast display technology is an efficient and highly sensitive method to identify binders to target antigens. This powerful selection tool, however, is often hampered by the typically modest size of yeast libraries (approximately 10(7)) due to the limited yeast transformation efficiency, and the full potential of the yeast display technology for antibody discovery and engineering can...

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PMID: 20130105
DOI: 10.1093/protein/gzq002

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