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Article

Expression and purification of a soluble B lymphocyte stimulator mutant modified with the T-helper cell epitope.

Biotechnology letters - 1 Oct 2006

Gao Huiguang, Fu Weiling, Li Rongfen, Chen Linfeng, Ji Qing, Zhang Li, Huang Gang, He Fengtian

Abstract excerpt

The DNA encoding soluble B lymphocyte stimulator (134-285 amino acids, sBLyS) mutant with residues 217-224 replaced by two glycines (named msBLyS) was constructed. The sequence encoding a foreign immunodominant T-helper epitope from ovalbumin (OVA) was then coupled to the 5'-end of msBLyS cDNA. A...

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Identifiers

PMID: 16902849
DOI: 10.1007/s10529-006-9139-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16902849-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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