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Article

Two observed regions in B lymphocyte stimulator important for its biological activity.

Acta biochimica et biophysica Sinica - 1 Apr 2006

Shen Qiong, Li Su-Xia, Fu Fei-Hao, Yuan Qin-Sheng, Gong Yi

Abstract excerpt

B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor superfamily of ligands, is a crucial survival factor for B cells. We successfully constructed seven mutants of the functional soluble fragment of human BLyS (named cBLyS, amino acid 134-285), including three deletion mutants and four site-directed mutants. All the mutant proteins were expressed in Escherichia coli and purified by Ni-NTA...

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PMID: 16604261
DOI: 10.1111/j.1745-7270.2006.00142.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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