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Article

Growth hormone injections improve bone quality in a mouse model of osteogenesis imperfecta.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2005

King Donna, Jarjoura David, McEwen Heather A, Askew Michael J

Abstract excerpt

UNLABELLED: Systemic growth hormone injections increased spine and femur length in a mouse model of OI. Femur BMC, cross-sectional area, and BMD were increased. Smaller gains were produced in vertebral BMC and cross-sectional area. Biomechanical testing showed improvements to structural and material properties in the femur midshaft, supporting expanded testing of growth hormone therapy in children with OI....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15883639
DOI: 10.1359/JBMR.050108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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