Article
A computational method to detect epistatic effects contributing to a quantitative trait.
Journal of theoretical biology - 7 Aug 2005
Hanlon Phil, Lorenz Andy
Abstract excerpt
We develop a new computational method to detect epistatic effects that contribute to a complex quantitative trait. Rather than looking for epistatic effects that show statistical significance when considered in isolation, we search for a close approximation to the quantitative trait by a sum of epistatic effects. Our search algorithm consists of a sequence of random walks around the space of sums of epistatic...
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