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Article

Rapid genotyping for relevant CYP1A2 alleles by pyrosequencing.

European journal of clinical pharmacology - 1 Dec 2005

Skarke Carsten, Kirchhof Anja, Geisslinger Gerd, Lötsch Jörn

Abstract excerpt

OBJECTIVE: To develop a rapid and reliable screening method for identifying the relevant cytochrome P450 (CYP) 1A2 alleles CYP1A2*1D (-2467Tdel), *1F (-163A>C), and *1K (-739T>G, -729C>T, -163A>C) that are in linkage disequilibrium with the functionally relevant CYP1A2 polymorphisms and therefore are considered to be predictive for the CYP1A2 phenotype. METHODS: CYP1A2 single nucleotide polymorphisms (SNPs)...

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Source

Identifiers

PMID: 16307269
DOI: 10.1007/s00228-005-0029-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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