Multiplex pyrosequencing method to determine CYP2C9*3, VKORC1*2, and CYP4F2*3 polymorphisms simultaneously: its application to a Korean population and comparisons with other ethnic groups.

doi:10.1007/s11033-014-3617-4

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Article

Multiplex pyrosequencing method to determine CYP2C93, VKORC12, and CYP4F2*3 polymorphisms simultaneously: its application to a Korean population and comparisons with other ethnic groups.

Molecular biology reports - 1 Nov 2014

Kim Kyoung-Ah, Song Wan-Geun, Lee Hae-Mi, Joo Hyun-Jin, Park Ji-Young

Abstract excerpt

Warfarin is an anticoagulant that is difficult to administer because of the wide variation in dose requirements to achieve a therapeutic effect. CYP2C9, VKROC1, and CYP4F2 play important roles in warfarin metabolism, and their genetic polymorphisms are related to the variability in dose determination. In this study we describe a new multiplex pyrosequencing method to identify CYP2C9*3 (rs1057910), VKORC1*2...

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Identifiers

PMID: 25069408
DOI: 10.1007/s11033-014-3617-4

Genes

VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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