Alginate acetylation influences initial surface colonization by mucoid Pseudomonas aeruginosa.

Abstract excerpt

Mucoid strains of Pseudomonas aeruginosa overproduce the exopolysaccharide alginate, which is substituted with O-acetyl groups. Under non-growing conditions in phosphate buffer, a mucoid clinical strain formed microcolonies on steel surfaces, while an acetylation-defective mutant was unable to form cell clusters. Enzymatic degradation of alginate by alginate lyase prevented microcolony formation of the mucoid...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acetylation
• Share to Alginates
• Share to Bacterial Adhesion