Article
AmrZ modulates Pseudomonas aeruginosa biofilm architecture by directly repressing transcription of the psl operon.
Journal of bacteriology - 1 Apr 2013
Jones Christopher J, Ryder Cynthia R, Mann Ethan E, Wozniak Daniel J
Abstract excerpt
Pseudomonas aeruginosa strains recovered from chronic pulmonary infections in cystic fibrosis patients are frequently mucoid. Such strains express elevated levels of alginate but reduced levels of the aggregative polysaccharide Psl; however, the mechanistic basis for this regulation is not completely understood. Elevated pslA expression was observed in an amrZ null mutant and in strains expressing a...
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