Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation.

The Journal of biological chemistry - 2 Aug 2013

Riley Laura M, Weadge Joel T, Baker Perrin, Robinson Howard, Codée Jeroen D C, Tipton Peter A, Ohman Dennis E, Howell P Lynne

Abstract excerpt

The exopolysaccharide alginate, produced by mucoid Pseudomonas aeruginosa in the lungs of cystic fibrosis patients, undergoes two different chemical modifications as it is synthesized that alter the properties of the polymer and hence the biofilm. One modification, acetylation, causes the cells in the biofilm to adhere better to lung epithelium, form microcolonies, and resist the effects of the host immune system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Alginates

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Crystallography, X-Ray

Share to Glucuronic Acid

Share to Hexuronic Acids

Share to Nuclear Magnetic Resonance, Biomolecular

Share to Protein Conformation

Share to Pseudomonas aeruginosa

Source

Open in PubMed Open full text

Identifiers

PMID: 23779107
DOI: 10.1074/jbc.M113.484931
PMCID: PMC3829321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation.PMID 23779107Read ↗

Evidence that the <i>algI</i> / <i>algJ</i> Gene Cassette, Required for O Acetylation of <i>Pseudomonas aeruginosa</i> Alginate, Evolved by Lateral Gene TransferSemantic proximity Read ↗

Alginate Polymerization and Modification Are Linked in Pseudomonas aeruginosa.Semantic proximity Read ↗

The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesisSemantic proximity Read ↗

MucD regulates alginate biosynthesis through the proteolytic control of AlgX and AlgK in Pseudomonas aeruginosaSemantic proximity Read ↗

Mutant Analysis and Cellular Localization of the AlgI, AlgJ, and AlgF Proteins Required for O Acetylation of Alginate in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

AlgX Is a Periplasmic Protein Required for Alginate Biosynthesis in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Biochemical analysis of alginate biosynthesis protein AlgX from Pseudomonas aeruginosa: purification of an AlgX-MucD (AlgY) protein complex.Semantic proximity Read ↗

Identification of algF in the alginate biosynthetic gene cluster of Pseudomonas aeruginosa which is required for alginate acetylation.Semantic proximity Read ↗

Understanding the control of <i>Pseudomonas aeruginosa</i> alginate synthesis and the prospects for management of chronic infections in cystic fibrosisSemantic proximity Read ↗

Acetylation of glucosyltransferases regulates Streptococcus mutans biofilm formation and virulenceSemantic proximity Read ↗

Atypical thioredoxin Patrx2 enhances alginate production in mucoid <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm FormationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.