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Article

The sigma factor AlgU plays a key role in formation of robust biofilms by nonmucoid Pseudomonas aeruginosa.

Journal of bacteriology - 1 Jun 2010

Bazire Alexis, Shioya Kouki, Soum-Soutéra Emmanuelle, Bouffartigues Emeline, Ryder Cynthia, Guentas-Dombrowsky Linda, Hémery Gaëlle, Linossier Isabelle, Chevalier Sylvie, Wozniak Daniel J, Lesouhaitier Olivier, Dufour Alain

Abstract excerpt

The extracytoplasmic function sigma factor AlgU of Pseudomonas aeruginosa is responsible for alginate overproduction, leading to mucoidy and chronic infections of cystic fibrosis patients. We investigated here the role of AlgU in the formation of nonmucoid biofilms. The algU mutant of P. aeruginosa PAO1 (PAOU) showed a dramatic impairment in biofilm formation under dynamic conditions. PAOU was defective both in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20348252
DOI: 10.1128/JB.01633-09
PMCID: PMC2901682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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