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Article

Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 <i>Pseudomonas aeruginosa</i> biofilms

16 Jun 2003

Abstract excerpt

The bacterium Pseudomonas aeruginosa causes chronic respiratory infections in cystic fibrosis (CF) patients. Such infections are extremely difficult to control because the bacteria exhibit a biofilm-mode of growth, rendering P. aeruginosa resistant to antibiotics and phagocytic cells. During the course of infection, P. aeruginosa usually undergoes a phenotypic switch to a mucoid colony, which is characterized by...

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PMID: 12810959
DOI: 10.1073/pnas.1231792100

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Source receipt: pubmed, retrieved 7 Sept 2026.

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