Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila melanogaster: a Model for the Study of DNA Damage Checkpoint Response

1 Apr 2005

Abstract excerpt

The cells of metazoans respond to DNA damage by either arresting their cell cycle in order to repair the DNA, or by undergoing apoptosis. This response is highly conserved across species, and many of the genes involved in this DNA damage response have been shown to be inactivated in human cancers. This suggests the importance of DNA damage response with regard to the prevention of cancer. The DNA damage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cell death mechanisms and regulation
Share to DNA Repair Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15879698
DOI: 10.1016/s1016-8478(23)13152-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila melanogaster: a Model for the Study of DNA Damage Checkpoint ResponsePMID 15879698Read ↗

DNA damage checkpoints and cancer.Semantic proximity Read ↗

Importance of DNA damage checkpoints in the pathogenesis of human cancersSemantic proximity Read ↗

Methods for analyzing checkpoint responses in Caenorhabditis elegans.Semantic proximity Read ↗

Cell cycle control, checkpoint mechanisms, and genotoxic stress.Semantic proximity Read ↗

[Relationship between abnormalities of genes involved in DNA damage responses and malignant tumors/autoimmune diseases].Semantic proximity Read ↗

DNA damage and cell cycle checkpointsSemantic proximity Read ↗

DNA damage responses and p53 in the aging processSemantic proximity Read ↗

Cell cycle checkpoint control mechanisms that can be disrupted in cancer.Semantic proximity Read ↗

p53-independent apoptosis limits DNA damage-induced aneuploidy.Semantic proximity Read ↗

Cell cycle control, DNA damage checkpoints and cancer.Semantic proximity Read ↗

<i>Drosophila p53</i> isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality controlSemantic proximity Read ↗

A method for assaying the sensitivity of Drosophila replication checkpoint mutants to anti-cancer and DNA-damaging drugs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.