Article
Phosphorylation of rap1GAP in vivo and by cAMP-dependent kinase and the cell cycle p34cdc2 kinase in vitro.
The Journal of biological chemistry - 25 May 1992
Polakis P, Rubinfeld B, McCormick F
Abstract excerpt
rap1GAP is a GTPase activating protein that specifically stimulates the GTP hydrolytic rate of the ras-related protein p21rap1.rap1GAP undergoes post-translational modification that causes a substantial change in its mobility on sodium dodecyl sulfate-polyacrylamide gels. At least part of this mo...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Western
- CDC2 Protein Kinase
- Cell Line
- Electrophoresis, Polyacrylamide Gel
- GTP-Binding Proteins
- GTPase-Activating Proteins
- Hydrolysis
- Insecta
- Kinetics
- Molecular Sequence Data
- Mutation
- Peptide Mapping
- Phosphorylation
- Protein Kinases
- Protein Processing, Post-Translational
- Proteins