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Article

FHOD1 coordinates actin filament and microtubule alignment to mediate cell elongation.

Experimental cell research - 15 May 2005

Gasteier Judith E, Schroeder Sebastian, Muranyi Walter, Madrid Ricardo, Benichou Serge, Fackler Oliver T

Abstract excerpt

Diaphanous-related formins (DRFs) are actin nucleators that mediate rearrangements of the actin cytoskeleton downstream of specific Rho GTPases. The DRF Formin Homology 2 Domain containing 1 (FHOD1) interacts with the Rac1 GTPase and induces the formation of and associates with bundled actin stress fibers. Here we report that active FHOD1 also coordinates microtubules with these actin stress fibers. Expression of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15878344
DOI: 10.1016/j.yexcr.2005.02.006

Genes

FHOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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