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Article

Drosophila and human FHOD family formin proteins nucleate actin filaments

10 Nov 2017

Abstract excerpt

Formins are a conserved group of proteins that nucleate and processively elongate actin filaments. Among them, the formin homology domain–containing protein (FHOD) family of formins contributes to contractility of striated muscle and cell motility in several contexts. However, the mechanisms by which they carry out these functions remain poorly understood. Mammalian FHOD proteins were reported not to accelerate...

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PMID: 29127202
DOI: 10.1074/jbc.m117.800888

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