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Article

Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1.

The Journal of biological chemistry - 24 Feb 2006

Schönichen André, Alexander Michael, Gasteier Judith E, Cuesta Fanny E, Fackler Oliver T, Geyer Matthias

Abstract excerpt

Diaphanous related formins (DRFs) are cytoskeleton remodeling proteins that mediate specific upstream GTPase signals to regulate cellular processes such as cytokinesis, cell polarity, and organelle motility. Previous work on the Rho-interacting DRF mDia has established that the biological activity of DRFs is regulated by an autoinhibitory interaction of a C-terminal diaphanous autoregulatory domain (DAD) with the...

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Source

Identifiers

PMID: 16361249
DOI: 10.1074/jbc.M509226200

Genes

FHOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1.PMID 16361249Read ↗

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