Article
DRhoGEF2 regulates actin organization and contractility in the Drosophila blastoderm embryo.
The Journal of cell biology - 14 Feb 2005
Padash Barmchi Mojgan, Rogers Stephen, Häcker Udo
Abstract excerpt
Morphogenesis of the Drosophila melanogaster embryo is associated with a dynamic reorganization of the actin cytoskeleton that is mediated by small GTPases of the Rho family. Often, Rho1 controls different aspects of cytoskeletal function in parallel, requiring a complex level of regulation. We show that the guanine triphosphate (GTP) exchange factor DRhoGEF2 is apically localized in epithelial cells throughout...
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