Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Apr 2005

Andreassen Christian Nicolaj, Alsner Jan, Overgaard Jens, Herskind Carsten, Haviland Jo, Owen Roger, Homewood Janis, Bliss Judith, Yarnold John

Abstract excerpt

Recent studies suggest that normal tissue radiosensitivity is influenced by single nucleotide polymorphisms (SNPs) in certain genes. In order to seek a confirmation of these findings, this study investigated SNPs in genes TGFB1 (position -509, codon 10 and codon 25), SOD2 (codon 16), XRCC1 (codon 399), XRCC3 (codon 241), APEX (codon 148) and ATM (codon 1853) in 26 breast cancer patients with marked changes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Staging

Share to Predictive Value of Tests

Share to Radiation Injuries

Share to Radiation Tolerance

Share to Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 15878096
DOI: 10.1016/j.radonc.2004.12.012

Genes

TGFB1
ATM
SOD2
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer.PMID 15878096Read ↗

Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes.Semantic proximity Read ↗

Association between normal tissue complications after radiotherapy and polymorphic variations in TGFB1 and XRCC1 genes.Semantic proximity Read ↗

Can risk of radiotherapy-induced normal tissue complications be predicted from genetic profiles?Semantic proximity Read ↗

Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity.Semantic proximity Read ↗

Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.Semantic proximity Read ↗

Test of association between variant tgβ1 alleles and late adverse effects of breast radiotherapy.Semantic proximity Read ↗

Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM--a study based on DNA from formalin fixed paraffin embedded tissue samples.Semantic proximity Read ↗

No association between TGFB1 polymorphisms and late radiotherapy toxicity: a meta-analysis.Semantic proximity Read ↗

TGFbeta1 (Leu10Pro), p53 (Arg72Pro) can predict for increased risk for breast cancer in south Indian women and TGFbeta1 Pro (Leu10Pro) allele predicts response to neo-adjuvant chemo-radiotherapy.Semantic proximity Read ↗

Common variants of GSTP1, GSTA1, and TGFβ1 are associated with the risk of radiation-induced fibrosis in breast cancer patients.Semantic proximity Read ↗

Association of transforming growth factor beta-1 single nucleotide polymorphisms with radiation-induced damage to normal tissues in breast cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.