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Article

An evolutionary scenario for genomic imprinting of Impact lying between nonimprinted neighbors.

DNA research : an international journal for rapid publication of reports on genes and genomes - 31 Dec 2004

Okamura Kohji, Yamada Yoichi, Sakaki Yoshiyuki, Ito Takashi

Abstract excerpt

Mouse Impact is the sole imprinted gene mapped to chromosome 18 to date. Despite its remarkable evolutionary conservation, human IMPACT was shown to escape genomic imprinting. Here we identified Hrh4 and Osbpl1 as the distal and proximal nearest neighbors of Impact, respectively, and found that both genes are expressed biallelically. Thus, in contrast with most imprinted genes, Impact fails to show apparent...

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Source

Identifiers

PMID: 15871461
DOI: 10.1093/dnares/11.6.381

Genes

IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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