Article
IMPACT and OSBPL1A are two isoform-specific imprinted genes in bovines.
Theriogenology - 1 May 2022
Dong Yanqiu, Jin Lanjie, Liu Xiaoqian, Li Dongjie, Chen Weina, Huo Haonan, Zhang Cui, Li Shijie
Abstract excerpt
The epigenetic process of genomic imprinting results in the monoallelic expression of genes based on their parental origin. Comparative analysis of imprinted genes between species is useful for investigating the biological significance and regulatory mechanisms of genomic imprinting. Mouse Impact is an imprinted gene, but its human ortholog IMPACT escapes genomic imprinting. Hrh4 and Osbpl1a are the two nearest...
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