Article
Characterization and imprinting status of OBPH1/Obph1 gene: implications for an extended imprinting domain in human and mouse.
Genomics - 1 Dec 2002
Higashimoto Ken, Soejima Hidenobu, Yatsuki Hitomi, Joh Keiichiro, Uchiyama Michiko, Obata Yayoi, Ono Ryuichi, Wang Youdong, Xin Zhenghan, Zhu Xike, Masuko Sadahiko, Ishino Fumitoshi, Hatada Izuho, Jinno Yoshihiro, Iwasaka Tsuyoshi, Katsuki Takeshi, Mukai Tsunehiro
Abstract excerpt
Human 11p15.5, as well as its orthologous mouse 7F4/F5, is known as the imprinting domain extending from IPL/Ipl to H19. OBPH1 and Obph1 are located beyond the presumed imprinting boundary on the IPL/Ipl side. We determined full-length cDNAs and complete genomic structures of both orthologues. We also investigated their precise imprinting and methylation status. The orthologues resembled each other in genomic...
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