Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.

Human molecular genetics - 22 Jul 2000

Paulsen M, El-Maarri O, Engemann S, Strödicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J

Abstract excerpt

In human and mouse most imprinted genes are arranged in chromosomal clusters. This linked organization suggests coordinated mechanisms controlling imprinted expression. We have sequenced 250 kb in the centre of the mouse imprinting cluster on distal chromosome 7 and compared it with the orthologous Beckwith-Wiedemann gene cluster on human chromosome 11p15.5. This first comparative imprinting cluster analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Beckwith-Wiedemann Syndrome
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to Genes, Tumor Suppressor

Share to Genomic Imprinting

Share to Multigene Family

Share to Tetraspanins

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 10915772
DOI: 10.1093/hmg/9.12.1829

Genes

TSSC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.PMID 10915772Read ↗

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprintingSemantic proximity Read ↗

Beckwith-Wiedemann syndrome: imprinting in clusters revisitedSemantic proximity Read ↗

Genomic Imprinting: Intricacies of Epigenetic Regulation in ClustersSemantic proximity Read ↗

Imprinting mechanisms in mammals.Semantic proximity Read ↗

The two-domain hypothesis in Beckwith–Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 clusterSemantic proximity Read ↗

Comparative analysis of sequence characteristics of imprinted genes in human, mouse, and cattleSemantic proximity Read ↗

Genomic Imprinting in Mammals: Emerging Themes and Established TheoriesSemantic proximity Read ↗

Imprinting in clusters: lessons from Beckwith-Wiedemann syndromeSemantic proximity Read ↗

Identification and characterisation of imprinted genes in the mouse.Semantic proximity Read ↗

Mechanisms of genomic imprinting.Semantic proximity Read ↗

Mechanisms regulating imprinted genes in clustersSemantic proximity Read ↗

Modeling human epigenetic disorders in mice: Beckwith-Wiedemann Syndrome and Silver-Russell SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.