Article
Expression of truncated latent TGF-beta-binding protein modulates TGF-beta signaling.
Journal of cell science - 15 May 2005
Mazzieri Roberta, Jurukovski Vladimir, Obata Hiroto, Sung Joanne, Platt Alec, Annes Eric, Karaman-Jurukovska Nevena, Gleizes Pierre-Emmanuel, Rifkin Daniel B
Abstract excerpt
Transforming growth factor-beta is released from most cells as an inactive complex consisting of transforming growth factor-beta, the transforming growth factor-beta propeptide and the latent transforming growth factor-beta-binding protein. We studied the role of latent transforming growth factor-beta-binding protein in modulating transforming growth factor-beta availability by generating transgenic mice that...
Topics
- Animals
- Animals, Newborn
- Cell Line, Tumor
- Cell Nucleus
- Cell Proliferation
- Extracellular Matrix
- Hair
- Humans
- Intracellular Signaling Peptides and Proteins
- Keratin-14
- Keratinocytes
- Keratins
- Latent TGF-beta Binding Proteins