Article
Function of cytokines within the TGF-beta superfamily as determined from transgenic and gene knockout studies in mice.
Current molecular medicine - 1 May 2002
Kulkarni Ashok B, Thyagarajan Tamizchelvi, Letterio John J
Abstract excerpt
Several major conceptual problems regarding specific in vivo functions of the TGF-beta family members remain the key focus of many researchers studying the biology of these secreted signaling molecules. More than 45 members of this family of growth factors have been identified and partially characterized for their molecular roles in numerous processes such as cell proliferation and differentiation, embryonic...
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