Article
A temperature-sensitive cell-cycle mutant of mammalian cells, tsJT16, is defective in a function operating soon after growth stimulation.
Cell structure and function - 1 Feb 1990
Takasuka T, Ninomiya-Tsuji J, Sakayama M, Ishibashi S, Ide T
Abstract excerpt
A temperature-sensitive cell-cycle mutant, tsJT16, which has been isolated from Fischer rat fibroblasts, was defective in the function(s) that operated soon after growth stimulation. When G0-arrested tsJT16 was stimulated to proliferate, it entered the S phase after 12-15 h at 34 degrees C but fa...
Topics
- Animals
- Blood Physiological Phenomena
- Blotting, Northern
- Cell Cycle
- Cell Division
- Cell Line
- Electrophoresis, Gel, Two-Dimensional
- Gene Expression Regulation
- Kinetics
- Mutation
- Protein Biosynthesis
- Proto-Oncogenes
- Temperature
- Transcriptional Activation
