Article
Soluble thrombomodulin activity and soluble thrombomodulin antigen in plasma.
Journal of thrombosis and haemostasis : JTH - 1 May 2005
Ohlin A-K, Larsson K, Hansson M
Abstract excerpt
Endothelial cell membrane-bound thrombomodulin (TM) plays a critical role as a cofactor in the protein C pathway, important in regulating coagulation as well as inflammation. Heterogeneous soluble TM fragments circulate in the plasma and are found at increased levels in various diseases such as cardiovascular disease and diabetes, and in ischemic and/or inflammatory endothelial injuries. The anticoagulant...
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