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Article

Stable expression of a secretable deletion mutant of recombinant human thrombomodulin in mammalian cells.

The Journal of biological chemistry - 25 Jul 1990

Parkinson J F, Grinnell B W, Moore R E, Hoskins J, Vlahos C J, Bang N U

Abstract excerpt

Thrombomodulin is an endothelial cell membrane protein which plays a central regulatory role in the protein C anticoagulant pathway. The human thrombomodulin intronless gene was isolated from a genomic DNA library and used to isolate the coding region. A mammalian expression vector, phd-TMD1, encoding all the extracellular domains of human thrombomodulin but lacking the transmembrane and cytoplasmic domains was...

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PMID: 2165069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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