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Article

Def1p is involved in telomere maintenance in budding yeast.

The Journal of biological chemistry - 1 Jul 2005

Chen Yong-Bin, Yang Cui-Ping, Li Rong-Xia, Zeng Rong, Zhou Jin-Qiu

Abstract excerpt

Saccharomyces Rrm3p, a member of Pif1 5'-3' DNA helicase subfamily, helps replication forks traverse protein-DNA complexes, including the telomere. Here we have identified an Rrm3p interaction protein known to be Def1p. In def1 mutants, telomeres were approximately 200-bp shorter than that in wild-type cells. DEF1 is also required for the stable maintenance of mitochondrial DNA, and the telomere shortening...

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Source

Identifiers

PMID: 15863512
DOI: 10.1074/jbc.M413562200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Def1p is involved in telomere maintenance in budding yeast.PMID 15863512Read ↗

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