Article
Mouse genetic background influences severity of immune responses following trauma-hemorrhage.
Cytokine - 21 May 2005
Matsutani Takeshi, Anantha Samy T S, Kang Shih-Ching, Bland Kirby I, Chaudry Irshad H
Abstract excerpt
Studies have shown that following bacterial infection or endotoxin administration, immune functions are regulated differently in mice of different genetic background. Since the susceptibility to sepsis following trauma-hemorrhage is dependant on the severity of injury, it is important to determine whether genetic background of the animal influence immune functions after trauma-hemorrhage. The aim of our studies,...
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