Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variability in the immune-inflammatory response after major burn injury.

Shock (Augusta, Ga.) - 1 Feb 2005

Schwacha Martin G, Holland Lawanda T, Chaudry Irshad H, Messina Joseph L

Abstract excerpt

Thermal injury induces immune dysfunction and alters numerous physiological parameters. Studies have proposed that genetics influence the outcome after traumatic injury and/or sepsis, however, the contribution of genetics to the immune-inflammatory response postburn has not been investigated. In this study, mice of three distinct genetic backgrounds (C57BL/6NCrlBR, BALB/cAnNCrlBR, and 129S6/SvEvTac) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Burns
Share to CD3 Complex
Share to Immune System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-2

Share to Nitric Oxide

Share to Spleen

Share to Th1 Cells

Share to Th2 Cells

Source

Identifiers

PMID: 15665726
DOI: 10.1097/01.shk.0000148073.19717.a9

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variability in the immune-inflammatory response after major burn injury.PMID 15665726Read ↗

Mouse genetic background influences severity of immune responses following trauma-hemorrhage.Semantic proximity Read ↗

Genetic determinants influencing the response to injury, inflammation, and sepsis.Semantic proximity Read ↗

Genetic control of the innate immune response.Semantic proximity Read ↗

A Multigenerational “Dirty” Mouse Model for Studying Trauma-Induced Immune Dysregulation and Infection SusceptibilitySemantic proximity Read ↗

Inflammation and the Host Response to Injury: An Overview of the Multicenter Study of the Genomic and Proteomic Response to Burn InjurySemantic proximity Read ↗

GENETIC COMPONENT IN THE INFLAMMATORY RESPONSE INDUCED BY BACTERIAL LIPOPOLYSACCHARIDESemantic proximity Read ↗

The genetics of innate immunity.Semantic proximity Read ↗

Differential immunological phenotypes are exhibited after scald and flame burns.Semantic proximity Read ↗

Mispairing C57BL/6 substrains of genetically engineered mice and wild-type controls can lead to confounding results as it did in studies of JNK2 in acetaminophen and concanavalin A liver injury.Semantic proximity Read ↗

Differential expression and tissue compartmentalization of the inflammatory response following thermal injury.Semantic proximity Read ↗

Experimental progressive emphysema in BALB/cJ mice as a model for chronic alveolar destruction in humansSemantic proximity Read ↗

The genotype of bone marrow-derived inflammatory cells does not account for differences in skeletal muscle regeneration between SJL/J and BALB/c mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.