Article
Genetic background determines metabolic phenotypes in the mouse.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2008
Champy Marie-France, Selloum Mohammed, Zeitler Valérie, Caradec Claudia, Jung Barbara, Rousseau Stéphane, Pouilly Laurent, Sorg Tania, Auwerx Johan
Abstract excerpt
To evaluate the contribution of genetic background to phenotypic variation, we compared a large range of biochemical and metabolic parameters at different ages of four inbred mice strains, C57BL/6J, 129SvPas, C3HeB/FeJ, and Balb/cByJ. Our results demonstrate that important metabolic, hematologic, and biochemical differences exist between these different inbred strains. Most of these differences are gender...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.