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Article

Common death receptor 4 (DR4) polymorphisms do not predispose to ovarian cancer.

Gynecologic oncology - 1 May 2005

Horak Peter, Pils Dietmar, Roessler Max, Tomek Sandra, Elandt Katarzyna, Zeillinger Robert, Zielinski Christoph, Krainer Michael

Abstract excerpt

OBJECTIVE: Polymorphisms of death receptor 4 (DR4) might impair the apoptotic signal transduction and lead to dysregulation of the homeostasis between cell survival and cell death, promoting tumor development and progression. METHODS: We performed an analysis of known DR4 polymorphisms, namely G442A, C626G, and A1322G, in germ line DNA of 97 ovarian cancer patients and controls as well as in established ovarian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15863153
DOI: 10.1016/j.ygyno.2005.01.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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