Article
Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population.
Cellular and molecular biology (Noisy-le-Grand, France) - 30 Oct 2015
Zahoor A, Mansoor Q, Farooqi A A, Fayyaz S, Naz G, Ismail M
Abstract excerpt
TRAIL mediated signaling in cancer cells has emerged as one amongst the most deeply studied molecular phenomenon. Data obtained through genetic studies has highlighted highly polymorphic nature of DR4 and in accordance with this concept, we aimed to investigate the association between Colorectal cancer and polymorphisms in TRAIL and DR4 gene. We selected 100 patients with colorectal cancer and 100 healthy, sex...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.