Article
Association of death receptor 4, Caspase 3 and 5 gene polymorphism with increased risk to bladder cancer in North Indians.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Aug 2011
Mittal R D, Srivastava P, Mittal T, Verma A, Jaiswal P K, Singh V, Mandal R K, Mandhani A
Abstract excerpt
PURPOSE: Perturbed apoptosis due to missense alterations in candidate tumor suppressor gene Death receptor 4 (DR4) and in caspases (Casp) lead to deregulated cell proliferation and cancer predisposition. Some data indicate that normal variations within the sequence of apoptotic genes may lead to suboptimal apoptotic capacity and therefore increased cancer risk. To test our proposal we examined whether six single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
