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Article

Human Concentrative Nucleoside Transporter 3 (hCNT3, SLC28A3) Forms a Cyclic Homotrimer.

Biochemistry - 11 Jul 2017

Stecula Adrian, Schlessinger Avner, Giacomini Kathleen M, Sali Andrej

Abstract excerpt

Many anticancer and antiviral drugs are purine or pyrimidine analogues, which use membrane transporters to cross cellular membranes. Concentrative nucleoside transporters (CNTs) mediate the salvage of nucleosides and the transport of therapeutic nucleoside analogues across plasma membranes by coupling the transport of ligands to the sodium gradient. Of the three members of the human CNT family, CNT3 has the...

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Identifiers

PMID: 28661652
DOI: 10.1021/acs.biochem.7b00339
PMCID: PMC6917504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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