Article
Strong linkage disequilibrium at the nucleotide analogue transporter ABCC5 gene locus.
Pharmacogenetics and genomics - 1 Feb 2005
Gwee Pai Chung, Tang Kun, Sew Pui Hoon, Lee Edmund J D, Chong Samuel S, Lee Caroline G L
Abstract excerpt
The ABCC5 transporter is a ubiquitously expressed ATP-dependent efflux pump that exports nucleotide analogues, including thiopurine anticancer drugs and antiviral drugs. Polymorphisms within this gene may be associated with differences in response to these drugs between different individuals. Haplotype mapping may facilitate the identification of causal genetic variations in association studies. Here, we report...
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