Article
Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population.
European journal of clinical pharmacology - 1 Apr 2005
Allabi Aurel C, Horsmans Yves, Issaoui Bouchra, Gala Jean-Luc
Abstract excerpt
OBJECTIVE: The ABCB1 (MDR1) multidrug transporter plays a key role in determining drug bioavailability. Differences in drug response exist among different ethnic groups. However, until now, no haplotype data are available in a Black African population. METHODS: Exons 2, 7, 10, 11, 12, 14, 17, 21, 26, and the surrounding intronic regions were sequenced using genomic DNA from 111 Beninese subjects to examine 19...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
