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Article

Analysis of quinolone resistance mechanisms in Neisseria gonorrhoeae isolates in vitro.

Sexually transmitted infections - 1 Feb 1998

Tanaka M, Sakuma S, Takahashi K, Nagahuzi T, Saika T, Kobayashi I, Kumazawa J

Abstract excerpt

BACKGROUND AND OBJECTIVES: Gonococcal fluoroquinolone resistance is now a significant problem in Japan. We generated gonococcal mutants resistant to norfloxacin in vitro from norfloxacin sensitive isolates and analysed the contribution of three known mechanisms of quinolone resistance in Neisseria gonorrhoeae. MATERIALS AND METHODS: Three clinical isolates of N gonorrhoeae susceptible to norfloxacin were exposed...

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Identifiers

PMID: 9634306
DOI: 10.1136/sti.74.1.59
PMCID: PMC1758082

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Source receipt: pubmed, retrieved 7 Sept 2026.

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