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Article

Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa.

Antimicrobial resistance and infection control - 5 Aug 2020

Zhao Lei, Wang Shiqi, Li Xiaobing, He Xiaojing, Jian Lingyan

Abstract excerpt

Fluoroquinolone resistance in Pseudomonas aeruginosa typically arises through site-specific mutations and overexpression of efflux pumps. In this study, we investigated the dynamics of different resistance mechanisms in P. aeruginosa populations that have evolved under fluoroquinolone pressure, as well as the interactions between these mechanisms in evolutionary trajectories. Bacteria of strain ATCC27853 were...

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Identifiers

PMID: 32758289
DOI: 10.1186/s13756-020-00793-8
PMCID: PMC7405379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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