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Article

Development of fluoroquinolone resistance and mutations involving GyrA and ParC proteins among Neisseria gonorrhoeae isolates in Japan.

The Journal of urology - 1 Jun 1998

Tanaka M, Takahashi K, Saika T, Kobayashi I, Ueno T, Kumazawa J

Abstract excerpt

PURPOSE: To investigate the development of fluoroquinolone resistance among Neisseria gonorrhoeae isolates in Japan and the frequency and patterns of mutations involving the GyrA and ParC proteins, which confer quinolone resistance to the bacteria, in isolates. MATERIALS AND METHODS: Antimicrobial susceptibilities of 145 gonococcal isolates, including 79 isolated from February 1992 through February 1993 and 66...

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PMID: 9598572
DOI: 10.1016/S0022-5347(01)63308-1

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