Article
Development of fluoroquinolone resistance and mutations involving GyrA and ParC proteins among Neisseria gonorrhoeae isolates in Japan.
The Journal of urology - 1 Jun 1998
Tanaka M, Takahashi K, Saika T, Kobayashi I, Ueno T, Kumazawa J
Abstract excerpt
PURPOSE: To investigate the development of fluoroquinolone resistance among Neisseria gonorrhoeae isolates in Japan and the frequency and patterns of mutations involving the GyrA and ParC proteins, which confer quinolone resistance to the bacteria, in isolates. MATERIALS AND METHODS: Antimicrobia...
Topics
- Acute Disease
- Anti-Infective Agents
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Fluoroquinolones
- Genes, Bacterial
- Humans
- Male
- Microbial Sensitivity Tests
- Mutation
- Neisseria gonorrhoeae
- Polymerase Chain Reaction
- Urethritis