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Article

Correlation of in vitro susceptibilities to newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains with changes in GyrA and ParC.

Antimicrobial agents and chemotherapy - 1 Mar 2001

Shultz T R, Tapsall J W, White P A

Abstract excerpt

The in vitro activities of ciprofloxacin, trovafloxacin, moxifloxacin, and grepafloxacin against 174 strains of Neisseria gonorrhoeae isolated in Sydney, Australia, were determined. The strains included 84 quinolone-less-sensitive and -resistant N. gonorrhoeae (QRNG) strains for which ciprofloxacin MICs were in the range of 0.12 to 16 microg/ml. The QRNG included strains isolated from patients whose infections...

Topics

Anti-Infective Agents
Ciprofloxacin
DNA Gyrase
DNA Topoisomerase IV
DNA Topoisomerases, Type II
Drug Resistance, Microbial
Fluoroquinolones
Humans
Microbial Sensitivity Tests
Naphthyridines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neisseria gonorrhoeae

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Identifiers

PMID: 11181352
DOI: 10.1128/AAC.45.3.734-738.2001
PMCID: PMC90365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11181352-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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