Article
Genetic study of ICAM1 in clinical malaria in Senegal.
Tissue antigens - 1 May 2005
Ndiaye R, Sakuntabhai A, Casadémont I, Rogier C, Tall A, Trape J-F, Spiegel A, Dieye A, Julier C
Abstract excerpt
Many genes have been implicated in the risk of severe malaria, generally based on candidate gene studies in case/control populations. Among these genes, there has been conflicting reports for the implication of a variant of the intercellular adhesion molecule 1 (ICAM1), ICAM1(Kilifi), in the risk of severe malaria, while in vitro studies provided independent support for a functional role of this variant. In order...
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