Article
Variations in host genes encoding adhesion molecules and susceptibility to falciparum malaria in India.
Malaria journal - 4 Dec 2008
Sinha Swapnil, Qidwai Tabish, Kanchan Kanika, Anand Prerna, Jha Ganga N, Pati Sudhanshu S, Mohanty Sanjib, Mishra Saroj K, Tyagi Prajesh K, Sharma Surya K, Venkatesh Vimala, Habib Saman
Abstract excerpt
BACKGROUND: Host adhesion molecules play a significant role in the pathogenesis of Plasmodium falciparum malaria and changes in their structure or levels in individuals can influence the outcome of infection. The aim of this study was to investigate the association of SNPs of three adhesion molecule genes, ICAM1, PECAM1 and CD36, with severity of falciparum malaria in a malaria-endemic and a non-endemic region of...
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