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Article

Variation in the ICAM1 gene is not associated with severe malaria phenotypes.

Genes and immunity - 1 Jul 2008

Fry A E, Auburn S, Diakite M, Green A, Richardson A, Wilson J, Jallow M, Sisay-Joof F, Pinder M, Griffiths M J, Peshu N, Williams T N, Marsh K, Molyneux M E, Taylor T E, Rockett K A, Kwiatkowski D P

Abstract excerpt

Evidence from autopsy and in vitro binding studies suggests that adhesion of erythrocytes infected with Plasmodium falciparum to the human host intercellular adhesion molecule (ICAM)-1 receptor is important in the pathogenesis of severe malaria. Previous association studies between polymorphisms...

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Source

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Identifiers

PMID: 18528404
DOI: 10.1038/gene.2008.38
PMCID: PMC2657869

Genes

ICAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18528404-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Variation in the ICAM1 gene is not associated with severe malaria phenotypes.PMID 18528404Read ↗

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Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese.Semantic proximity Read ↗

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