Article
Genetic determination and linkage mapping of Plasmodium falciparum malaria related traits in Senegal.
PloS one - 23 Apr 2008
Sakuntabhai Anavaj, Ndiaye Rokhaya, Casadémont Isabelle, Peerapittayamongkol Chayanon, Peerapittayamonkol Chayanon, Rogier Christophe, Tortevoye Patricia, Tall Adama, Paul Richard, Turbpaiboon Chairat, Phimpraphi Waraphon, Trape Jean-Francois, Spiegel André, Heath Simon, Mercereau-Puijalon Odile, Dieye Alioune, Julier Cécile
Abstract excerpt
Plasmodium falciparum malaria episodes may vary considerably in their severity and clinical manifestations. There is good evidence that host genetic factors contribute to this variability. To date, most genetic studies aiming at the identification of these genes have used a case/control study design for severe malaria, exploring specific candidate genes. Here, we performed a family-based genetic study of...
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