Article
Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis.
Molecular biology & medicine - 1 Jun 1990
Matsubara K, Tokino T
Abstract excerpt
Hepatitis B virus (HBV) DNA integrates into human hepatocyte DNA. We have gathered the available data on the structure of the integrants from human hepatocellular carcinomas, and classified them into those that seem to represent primary integrants and those that are the products of secondary rearrangements. By means of structural analyses of the possible primary integrants, we deduced that the replication...
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