Article
Role of Protein Glycosylation in Candida parapsilosis Cell Wall Integrity and Host Interaction
8 Mar 2016
Abstract excerpt
Candida parapsilosis is an important, emerging opportunistic fungal pathogen. Highly mannosylated fungal cell wall proteins are initial contact points with host immune systems. In Candida albicans, Och1 is a Golgi α1,6-mannosyltransferase that plays a key role in the elaboration of the N-linked mannan outer chain. Here, we disrupted C. parapsilosis OCH1 to gain insights into the contribution of N-linked...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
