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Article

The MP65 gene is required for cell wall integrity, adherence to epithelial cells and biofilm formation in Candida albicans

1 Jan 2011

Abstract excerpt

BACKGROUND: The MP65 gene of Candida albicans (orf19.1779) encodes a putative β-glucanase mannoprotein of 65 kDa, which plays a main role in a host-fungus relationship, morphogenesis and pathogenicity. In this study, we performed an extensive analysis of a mp65Δ mutant to assess the role of this protein in cell wall integrity, adherence to epithelial cells and biofilm formation. RESULTS: The mp65Δ mutant showed a...

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PMID: 21575184
DOI: 10.1186/1471-2180-11-106

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